At first, I felt absolutely miserable when doing so, it is the worst Ive felt in my life and I was unable to do almost anything but after some weeks it became more tolerable as the receptors lost some of their sensitivity. Post-finasteride syndrome (PFS) is defined as a syndrome with symptoms that can include erectile dysfunction (ED), decreased libido, fatigue, penile and scrotal atrophy and numbness, gynecomastia, muscle atrophy, anxiety, blunted affect, and emotional sensitivity in patients who have taken 5-reductase inhibitors such as finasteride or On PFS forums, peoples dicks got 1 inch bigger when erect, here and there, they sometimes felt sexual attraction towards women. The guy who made this thread and gave his opinion was banned too. The supplement is making real changes in my body and mind, and it feels incredible. Ferri FF. Elsevier; 2022. https://www.clinicalkey.com. I understand not wanting to have a bunch of hack cures on their forum that dont really do anything or worse yet, make people worse, but at some point when theres a condition we dont know how to fix it seems like some trial and error wouldnt be the worst idea in the world. 2015;104:107. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron. Your doctor might also do a physical exam that includes examining your penis, testicles and rectum. Key takeaways: Finasteride is an FDA-approved medication that treats hair loss in men. However, the side effects of a medication usually go away when you stop taking it. "I had a case of PFS that was a severe as it gets. Of course there are some people with severe pfs but even then just wait is shit advice. Talking with a counselor might help. .ehsOqYO6dxn_Pf9Dzwu37{margin-top:0;overflow:visible}._2pFdCpgBihIaYh9DSMWBIu{height:24px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu{border-radius:2px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:focus,._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:hover{background-color:var(--newRedditTheme-navIconFaded10);outline:none}._38GxRFSqSC-Z2VLi5Xzkjy{color:var(--newCommunityTheme-actionIcon)}._2DO72U0b_6CUw3msKGrnnT{border-top:none;color:var(--newCommunityTheme-metaText);cursor:pointer;padding:8px 16px 8px 8px;text-transform:none}._2DO72U0b_6CUw3msKGrnnT:hover{background-color:#0079d3;border:none;color:var(--newCommunityTheme-body);fill:var(--newCommunityTheme-body)} I tried proviron for a short time but it made me feel worse. I cannot say enough about this. In: Campbell-Walsh-Wein Urology. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Medications might work for retrograde ejaculation caused by nerve damage. Yeah, yeah. Im suffering from pfs for 3+ years now so pfs is very real sadly but I believe the dudes article is the best explenation Ive read so far. Feeling dissociated and never present. official website and that any information you provide is encrypted In: Ferri's Clinical Advisor 2022. This is a summary of the protocol which I followed for 6 months which eventually cured me. I did a cycle of hcg 250ui m/w/f for 6 months + a week and a half of clomid 25 everyday + DHEA (I know I'm a idiot) More or less cured me from no low libido and all that great stuff for over a year now and I'm off everything. Public Health. Crazy. WebIn addition to the sexual, mental and physical side effects, PK suffers from miscellaneous issues connected with PFS. While we do connect people with vetted, board-certified doctors, we dont provide medical consultations, diagnosis, or advice. Write down key personal information, including prior surgeries or pelvic radiation, any major stresses, or recent life changes. Although these drugs are generally well tolerated, many reports described adverse effects in men during treatment, such as sexual dysfunction and mood alteration. Finasteride is available as a lower-cost generic. https://old.reddit.com/r/PostFinSyndrome/comments/ogcsjc/i_recovered_from_pfs_it_is_possible/. 2011 Mar;8(3):872-84. doi: 10.1111/j.1743-6109.2010.02157.x. Essentially I took testosterone exogenously And I took hcg afterwards, https://old.reddit.com/r/PSSD/comments/7lfc1e/how_i_fixed_my_pssd/. But on day 3, I felt like my old self. Next steps is likely getting a Hey there, Do a physical exam, which will likely include an exam of your penis, testicles and rectum.
Post-Finasteride Syndrome: Current Views and Where do we Stand? Understanding all of your options and communicating with your doctor and partner can help.
Fertil Steril.
Finasteride oral tablet I did a limited search and did not find other such claims. Here's some information to help you get ready for your appointment, and what to expect from your doctor. Endocrinol. /*# sourceMappingURL=https://www.redditstatic.com/desktop2x/chunkCSS/IdCard.ea0ac1df4e6491a16d39_.css.map*/._2JU2WQDzn5pAlpxqChbxr7{height:16px;margin-right:8px;width:16px}._3E45je-29yDjfFqFcLCXyH{margin-top:16px}._13YtS_rCnVZG1ns2xaCalg{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;display:-ms-flexbox;display:flex}._1m5fPZN4q3vKVg9SgU43u2{margin-top:12px}._17A-IdW3j1_fI_pN-8tMV-{display:inline-block;margin-bottom:8px;margin-right:5px}._5MIPBF8A9vXwwXFumpGqY{border-radius:20px;font-size:12px;font-weight:500;letter-spacing:0;line-height:16px;padding:3px 10px;text-transform:none}._5MIPBF8A9vXwwXFumpGqY:focus{outline:unset} I did this for 6 months straight but at the 10th week or so, the improvements were weekly. I need to get back over there and check it out I guess. This is to be expected because you are messing with a hormone (DHT) that is very important for sexual function. Press question mark to learn the rest of the keyboard shortcuts. | How To Diagnose And Reverse It. Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight lossfrom exercises to build a stronger core to advice on treating cataracts. more https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal Retrograde ejaculation can be especially challenging if you and your partner want to conceive a child. I know it's been a LONG time and also want to tell everyone that I'm cured from PFS great news. Careers. I has numbness also. A review of the FAERS data on 5-alpha reductase inhibitors: implications for postfinasteride syndrome. And youre competely right, they make it sound like youre doomed and you shouldnt try anything but wait for the Baylor study and fill out the surveyDo they really expect some magical cure to come out when Baylor releases or their survey has enough participants? Pharmacological Management of Pattern Hair Loss. https://old.reddit.com/r/FinasterideSyndrome/comments/psjeuu/could_trying_finasteride_for_1_month_be_harmfull/he38hlf/. PMC
Finasteride I was one of the lucky guys who recovered from Test injections, https://old.reddit.com/r/steroids/comments/igyd61/offtopic_daily_chat_20200826/g2ym80n/. BONUS! I haven't had that sort of performance since I was 19 or 20 years old. The mods on that forum are fascists and dont allow the opinion and theory of other people. Perhaps if I had tried it longer it would have helped more, Im not sure. Midodrine, a medicine that constricts blood vessels, Chlorpheniramine and brompheniramine, antihistamines that help relieve allergies, Ephedrine, pseudoephedrine and phenylephrine, medicines that help relieve symptoms of the common cold. I understand theyre trying to cover their ass but its the users responsibility if he wants to try it or not so the forum is not liable at all. More than a primer on prostate conditions, this Special Health Report, the Annual Report on Prostate Diseases, includes roundtable discussions with experts at the forefront of prostate research, interviews with men about their treatment decisions, and the latest thinking on complementary therapies. 2022 Jul 27;15(8):930. doi: 10.3390/ph15080930. Press J to jump to the feed. You're right. ._1sDtEhccxFpHDn2RUhxmSq{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;display:-ms-flexbox;display:flex;-ms-flex-flow:row nowrap;flex-flow:row nowrap}._1d4NeAxWOiy0JPz7aXRI64{color:var(--newCommunityTheme-metaText)}.icon._3tMM22A0evCEmrIk-8z4zO{margin:-2px 8px 0 0} https://www.amazon.com/reviews/R3OGTPUQ1CP005. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER).
Chicago Man: Taking Propecia is the Biggest Regret This site complies with the HONcode standard for trustworthy health information: verify here. But it is a risk men should discuss with their doctor prior to starting finasteride.
Finally Cured From Post Finasteride Syndrome | Ray Peat ._1EPynDYoibfs7nDggdH7Gq{margin-bottom:8px;position:relative}._1EPynDYoibfs7nDggdH7Gq._3-0c12FCnHoLz34dQVveax{max-height:63px;overflow:hidden}._1zPvgKHteTOub9dKkvrOl4{font-family:Noto Sans,Arial,sans-serif;font-size:14px;line-height:21px;font-weight:400;word-wrap:break-word}._1dp4_svQVkkuV143AIEKsf{-ms-flex-align:baseline;align-items:baseline;background-color:var(--newCommunityTheme-body);bottom:-2px;display:-ms-flexbox;display:flex;-ms-flex-flow:row nowrap;flex-flow:row nowrap;padding-left:2px;position:absolute;right:-8px}._5VBcBVybCfosCzMJlXzC3{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:21px;color:var(--newCommunityTheme-bodyText)}._3YNtuKT-Is6XUBvdluRTyI{position:relative;background-color:0;color:var(--newCommunityTheme-metaText);fill:var(--newCommunityTheme-metaText);border:0;padding:0 8px}._3YNtuKT-Is6XUBvdluRTyI:before{content:"";position:absolute;top:0;left:0;width:100%;height:100%;border-radius:9999px;background:var(--newCommunityTheme-metaText);opacity:0}._3YNtuKT-Is6XUBvdluRTyI:hover:before{opacity:.08}._3YNtuKT-Is6XUBvdluRTyI:focus{outline:none}._3YNtuKT-Is6XUBvdluRTyI:focus:before{opacity:.16}._3YNtuKT-Is6XUBvdluRTyI._2Z_0gYdq8Wr3FulRLZXC3e:before,._3YNtuKT-Is6XUBvdluRTyI:active:before{opacity:.24}._3YNtuKT-Is6XUBvdluRTyI:disabled,._3YNtuKT-Is6XUBvdluRTyI[data-disabled],._3YNtuKT-Is6XUBvdluRTyI[disabled]{cursor:not-allowed;filter:grayscale(1);background:none;color:var(--newCommunityTheme-metaTextAlpha50);fill:var(--newCommunityTheme-metaTextAlpha50)}._2ZTVnRPqdyKo1dA7Q7i4EL{transition:all .1s linear 0s}.k51Bu_pyEfHQF6AAhaKfS{transition:none}._2qi_L6gKnhyJ0ZxPmwbDFK{transition:all .1s linear 0s;display:block;background-color:var(--newCommunityTheme-field);border-radius:4px;padding:8px;margin-bottom:12px;margin-top:8px;border:1px solid var(--newCommunityTheme-canvas);cursor:pointer}._2qi_L6gKnhyJ0ZxPmwbDFK:focus{outline:none}._2qi_L6gKnhyJ0ZxPmwbDFK:hover{border:1px solid var(--newCommunityTheme-button)}._2qi_L6gKnhyJ0ZxPmwbDFK._3GG6tRGPPJiejLqt2AZfh4{transition:none;border:1px solid var(--newCommunityTheme-button)}.IzSmZckfdQu5YP9qCsdWO{cursor:pointer;transition:all .1s linear 0s}.IzSmZckfdQu5YP9qCsdWO ._1EPynDYoibfs7nDggdH7Gq{border:1px solid transparent;border-radius:4px;transition:all .1s linear 0s}.IzSmZckfdQu5YP9qCsdWO:hover ._1EPynDYoibfs7nDggdH7Gq{border:1px solid var(--newCommunityTheme-button);padding:4px}._1YvJWALkJ8iKZxUU53TeNO{font-size:12px;font-weight:700;line-height:16px;color:var(--newCommunityTheme-button)}._3adDzm8E3q64yWtEcs5XU7{display:-ms-flexbox;display:flex}._3adDzm8E3q64yWtEcs5XU7 ._3jyKpErOrdUDMh0RFq5V6f{-ms-flex:100%;flex:100%}._3adDzm8E3q64yWtEcs5XU7 .dqhlvajEe-qyxij0jNsi0{color:var(--newCommunityTheme-button)}._3adDzm8E3q64yWtEcs5XU7 ._12nHw-MGuz_r1dQx5YPM2v,._3adDzm8E3q64yWtEcs5XU7 .dqhlvajEe-qyxij0jNsi0{font-size:12px;font-weight:700;line-height:16px;cursor:pointer;-ms-flex-item-align:end;align-self:flex-end;-webkit-user-select:none;-ms-user-select:none;user-select:none}._3adDzm8E3q64yWtEcs5XU7 ._12nHw-MGuz_r1dQx5YPM2v{color:var(--newCommunityTheme-button);margin-right:8px;color:var(--newCommunityTheme-errorText)}._3zTJ9t4vNwm1NrIaZ35NS6{font-family:Noto Sans,Arial,sans-serif;font-size:14px;line-height:21px;font-weight:400;word-wrap:break-word;width:100%;padding:0;border:none;background-color:transparent;resize:none;outline:none;cursor:pointer;color:var(--newRedditTheme-bodyText)}._2JIiUcAdp9rIhjEbIjcuQ-{resize:none;cursor:auto}._2I2LpaEhGCzQ9inJMwliNO,._42Nh7O6pFcqnA6OZd3bOK{display:inline-block;margin-left:4px;vertical-align:middle}._42Nh7O6pFcqnA6OZd3bOK{fill:var(--newCommunityTheme-button);color:var(--newCommunityTheme-button);height:16px;width:16px;margin-bottom:2px} The Baylor study STILL hasnt been released? This is because (in the USA) it is only approved for BPH at 5mg and insurance companies will reject claims when it is prescibed at 1mg, which is the only other available dosage. I took a step back and said forget about PFS with these blood tests and these symptoms, whats the normal course of action? Preparing a list of questions before your appointment can help you make the most of your time together. Ejaculation and orgasm disorders. Hum. Your doctor might also ask about any health problems, surgeries or cancers you've had and what medications you take. I'm not going to go into the entire history of what post finasteride syndrome is, and I assume many of you looking into buying Tribulus know exactly what it is. National Library of Medicine
post-finasteride syndrome I do not think we have an answer to that question one way or the other. Palliative care frightens some people: Heres how it helps, Parents don't always realize that their teen is suicidal. Advertising revenue supports our not-for-profit mission. Alterations in orgasm are linked with lower emotional and physical satisfaction, which might lead to stress for you and your partner. I didnt feel any improvement and felt worse during that period but after that period I healed which is very weird. What the hell? The results have been amazing and far too great to chalk it up to just being a placebo. The management of retrograde ejaculation: A systematic review and update. After taking 50mg of Proviron I got my first erection in years. For details, see text. Crazy, but true! I did the first day 300 mg clomid, then 100mg for the first two weeks, 50mg for the third week, and none for the forth week. 2016 Sep;13(9):1297-1310. doi: 10.1016/j.jsxm.2016.07.006. Therefore, results here discussed indicate that PFS is an emerging clinical problem that needs to be further elucidated.
What Is Post-Finasteride Syndrome? - GoodRx Adverse effects of 5-reductase inhibitors: What do we know, don't know, and need to know? Anejaculation and retrograde ejaculation. I haven't introduced any other supplements or medications. Last time I was on there they had started discussing some relationships between HCG and Thyroid? These include: Prostate pain Persistent fatigue, exhaustion Stomach pains and digestive problems Constipation Blurry vision Propecia is the Biggest Regret of my Life Taking Propecia is the biggest regret of my life, PK said. And posted the article and some cliffs about his solution. I'm not going to go into the entire history of what post finasteride syndrome is, and I assume many of you looking into buying Tribulus know exactly what it is. However, the side effects of a medication usually go away when you stop taking it. His article with all the studies hes referencing: Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. Around 8 months and i was pretty much recovered. No active 34 year old man should have to be having ED discussions with his physician. Epub 2016 Jul 27. Stopping finasteride treatment can cause post-finasteride syndrome. This may result in side effects such as memory problems or sexual dysfunction (problems that affect the desire for or ability to have sex). Post-finasteride syndrome wasnt reported in clinical studies, but it has been reported since the drug was approved. To diagnose retrograde ejaculation, your doctor may: If you have dry orgasms, but your doctor doesn't find semen in your bladder, you might have a problem with semen production. I had all the classic symptoms. ._9ZuQyDXhFth1qKJF4KNm8{padding:12px 12px 40px}._2iNJX36LR2tMHx_unzEkVM,._1JmnMJclrTwTPpAip5U_Hm{font-size:16px;font-weight:500;line-height:20px;color:var(--newCommunityTheme-bodyText);margin-bottom:40px;padding-top:4px;text-align:left;margin-right:28px}._2iNJX36LR2tMHx_unzEkVM{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex}._2iNJX36LR2tMHx_unzEkVM ._24r4TaTKqNLBGA3VgswFrN{margin-left:6px}._306gA2lxjCHX44ssikUp3O{margin-bottom:32px}._1Omf6afKRpv3RKNCWjIyJ4{font-size:18px;font-weight:500;line-height:22px;border-bottom:2px solid var(--newCommunityTheme-line);color:var(--newCommunityTheme-bodyText);margin-bottom:8px;padding-bottom:8px}._2Ss7VGMX-UPKt9NhFRtgTz{margin-bottom:24px}._3vWu4F9B4X4Yc-Gm86-FMP{border-bottom:1px solid var(--newCommunityTheme-line);margin-bottom:8px;padding-bottom:2px}._3vWu4F9B4X4Yc-Gm86-FMP:last-of-type{border-bottom-width:0}._2qAEe8HGjtHsuKsHqNCa9u{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-bodyText);padding-bottom:8px;padding-top:8px}.c5RWd-O3CYE-XSLdTyjtI{padding:8px 0}._3whORKuQps-WQpSceAyHuF{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px}._1Qk-ka6_CJz1fU3OUfeznu{margin-bottom:8px}._3ds8Wk2l32hr3hLddQshhG{font-weight:500}._1h0r6vtgOzgWtu-GNBO6Yb,._3ds8Wk2l32hr3hLddQshhG{font-size:12px;line-height:16px;color:var(--newCommunityTheme-actionIcon)}._1h0r6vtgOzgWtu-GNBO6Yb{font-weight:400}.horIoLCod23xkzt7MmTpC{font-size:12px;font-weight:400;line-height:16px;color:#ea0027}._33Iw1wpNZ-uhC05tWsB9xi{margin-top:24px}._2M7LQbQxH40ingJ9h9RslL{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px}
A. Finasteride (sold as Proscar and generic brands) is prescribed for symptoms of an enlarged prostate; it's also used at a lower strength (under the name Propecia) for male pattern baldness. Do you have cloudy urine after an orgasm? Li X, Guo Y, Lu Y, Li H, Yan S, Li H, Li Y. Transl Androl Urol. I had all the classic symptoms. I was able to have 8 sexual encounters in 1 week with different people - I felt no PFS symptoms whatsoever My muscle mass and body fat composition is now normal, my semen thickened, Peyronies stabilized, penis pain subsided, testicular pain is rare cognitive issues are resolved, and overall I think I've bounced back almost entirely. Long term HCG treatment at high dosages can cause issues. Waitttt wait wait. Partin AW, et al., eds. Hcg I did 3000iu the first day then 250iu every other day for the four weeks. However, minoxidil is used "off-label" for treating telogen effluvium, scarring alopecia and alopecia areata. Getting to the root cause of your hairloss would be the first thing to do as if you have an underlying medical condition, once thats treated, it could reverse the hairloss, so definately get a consultation with a physician to rule out anything treatable. Accessed Oct. 28, 2021. 2016;93:9. When seeing your doctor for dry ejaculation the primary sign of retrograde ejaculation some basic questions to ask your doctor include: If you're trying to get your female partner pregnant, you might also want to ask: In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask additional questions during your appointment.
Post-finasteride Syndrome 2019;16 doi: 10.3390/ijerph16101726. Yeah, that guy's comment history is really puzzling: When i dared visit PFS forums, the most miserable users there were still in a better state than me. https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal-optimization/. Before Energy-boosting coffee alternatives: What to know. For details, see text., Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. Is Post Finasteride Syndrome Real? Do you ever ejaculate semen when you have an orgasm, or do you have a dry orgasm every time?
Post-Finasteride Syndrome: how to resolve it by Finally Cured From Post Finasteride Syndrome Its like they want to hide possible solutions. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Biomolecules. Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: These medications help keep the bladder neck muscle closed during ejaculation.
reddit Accessibility https://forum.propeciahelp.com/t/cured-after-11-years/42363. Is there a generic alternative to the medicine you're prescribing me? In addition, it has been also reported that persistent side effects may occur in some AGA patients.
Post-Finasteride Syndrome: What is It? | hims 2022 Oct;11(10):1452-1457. doi: 10.21037/tau-22-92.
Post-finasteride syndrome: a surmountable challenge for Feeling low-grade depression constantly.
Finasteride Side Effects After Stopping: PFS & What Are They? I suspect its because my E2 was so low already and that made it feel even lower (single digits if I recall correctly).
Post-finasteride syndrome - ScienceDirect ._3Z6MIaeww5ZxzFqWHAEUxa{margin-top:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._3EpRuHW1VpLFcj-lugsvP_{color:inherit}._3Z6MIaeww5ZxzFqWHAEUxa svg._31U86fGhtxsxdGmOUf3KOM{color:inherit;fill:inherit;padding-right:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._2mk9m3mkUAeEGtGQLNCVsJ{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;color:inherit} Finasteride blocks the metabolism of testosterone. That's one of the mildest forms of PFS you can experience. Your doctor will ask you questions about your health and symptoms. Toxicol. And yeah I know hackstasis, looks to be a much better community and forum than propeciahelp without fascist mods. I'll never be without this stuff again. Althof HE, et al. Note that prior to this protocol I tried injectable Test enanthate, Masteron, proviron and hcg which made my condition even worse. If medication doesn't allow you to ejaculate semen, you will likely need infertility procedures known as assisted reproductive technology to get your partner pregnant. Eliminate Trigger Foods. https://forum.propeciahelp.com/t/joekool-s-story-long-term-hcg/46717. 2008;35:211. Most men eventually develop some type of prostate problem, and when they do there are usually no easy solutions. It can cause bladder and urination problems. reading time: 43 Therefore, I cut the pills in half (2.5mg) and toss the other half. Drugs generally won't help if retrograde ejaculation is due to surgery that causes permanent physical changes of your anatomy. Since it only comes in 5 and 1 mg pills, there isnt much of a choice. Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects. Adverse side effects of 5-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients.
My personal experience is that finasteride is an important medication for older guys on TRT that are experiencing BPH. The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School. PFS is a very real, complex and multi-faceted thing - as is the human body. Are there other possible causes for my symptoms or condition?